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  • Human lactation research started (Neville/Neifert)

  • Human milk nutrition research started (Krebs/Hambidge)

1980's

  • Cellular and metabolic regulation of milk lipid secretion started (McManaman/Neville/Anderson)

  • Transcytosis mechanisms identified (Monks/Neville)

  • First use of proteomics to define milk lipid secretion (McManaman)

  • Phagocytotic function of mammary epithelial cells identified (Monks/Fadok)

  • First use of RNA expression profiling to define mammary gland functional development (Neville/Rudolph/McManaman) 

2000's

  • Molecular mechanisms of milk lipid secretion identified by mouse genetics (McManaman/Monks)

  • First use of single cell RNA sequencing to identify human milk cellular composition (Martin Carli/Rudolph/ Monks/MacLean/McManaman)

  • Identification of cellular functions in human milk fat globules (Martin Carli /Monks/McManaman)

  • Lactation initiation is shown to depend on milk lipid secretion (Monks/McManaman)

  • Mammary gland structure defined by AI (Monks)

2020's

1970's

Mammary gland ion transport studies started (Neville)

1990's

  • Molecular mechanisms of milk lipid secretion started (Neville/Neifert)

  • Regulation of mammary gland tight junctions identified (Neville)

2010's

  • Role of insulin signaling in mammary gland differentiation identified (Neville/Maclean)

  • Role of molecular structure in milk lipid secretion identified (McManaman)

  • Identification of diet and obesity effects on lactation (McManaman/MacLean)

  • First use of high-resolution 3D electron tomography to demonstrate that milk lipids originate from novel endoplasmic reticulum domains (McManaman/Howell)

Margaret Cobb Neville, PhD  (Peggy)

PeggyPic.jpg

Grants:

Trainees:

All P01 PIs
post-docs- links to webpages: Mike Lewis
grad students- links to webpages: Jen Monks, 

Pictures throughout the years

GRC_Colorado_edited.jpg
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